Better Science Starts with a Better Scaffold
Bio-Spun™ Inserts & HTS Plates — Engineered for Results, No Reruns
Why risk wasting time, inconsistent models, and repeated experiments?
Bio-Spun™ scaffolds deliver tissue-like performance that traditional cell culture tools can’t match.
The Bio-Spun™ Advantage
A scaffold proven to integrate — in vitro and in vivo.
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In Vivo–Validated Performance: First in vitro platform proven in animal studies for cell integration
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Improved Cell Retention: Maintains barrier integrity and viability through long-term culture
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Reduced Variability: Consistent, tissue-like environments produce cleaner, more reproducible data
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Flexible Formats: Available in 6-, 12-, and 24-well inserts, as well as 24- and 96-well HTS plates
Bio-Spun™ inserts pay for themselves in one successful experiment that would’ve otherwise failed.
Current Tissue Models Made with Bio-Spun™ Scaffolds
Airway Model
H&E-stained cross section of full-thickness human bronchial epithelial model produced on Bio-Spun™ PET Scaffold. The scaffold is populated with pulmonary fibroblasts which produce a fully human derived subepithelial matrix component. The fully developed pseudostratified mucociliary epithelium contains basal, goblet and ciliated cells with functional tight junctions.
Intestinal Model
H&E-stained cross section of human Intestinal epithelial model produced on Bio-Spun™ PDLGA Scaffold. The stratified differentiated intestinal epithelium contains villi- and crypt-like structures, contains enterocytes, goblet cells, and Paneth cells and develops functional tight junctions.
Retinal Model
H&E-stained cross section of engineered 3D outer blood retinal barrier (3D-oBRB) using Bio-Spun™ PDLGA. The scaffold is used to support the development of the 3D-oBRB. By 6 weeks, the tissue has reached maturity with RPE pigmentation (RPE), capillaries (cl) and Bruch's membrane (BM) formation.
Skin Model
H&E-stained cross section of full thickness human skin model produced on Bio-Spun™ PET Scaffold. Extracellular matrix proteins produced by keratinocytes and fibroblasts self-assemble to form a robust dermal component and basement membrane structures. The epidermis contains a uniform basal keratinocyte layer, granular cell layer, and stratum corneum layer with in vivo-like barrier function.
Call to Action
Experience the difference in your next experiment.
Explore our Bio-Spun™ In Vitro Research Tools line — featuring 6-, 12-, and 24-well individual inserts, along with ready-to-use 24- and 96-well HTS plates. Distributor discounts are available.